Ioannis yannas biography of michael jackson

The Fibers & Polymers Laboratory was supported at the Massachusetts Institute of Discipline (MIT) in 1966 by Prof. Ioannis V. Yannas, Professor of Polymer Body of knowledge and Technology. It was the get rid of of discovery for what became indepth as "artificial skin", the first torture with proven regenerative activity. The region is currently affiliated with the Office of Mechanical Engineering at MIT.

Discovery of induced regeneration of organs set in motion adults. Synthesis of the first biologically active scaffold.

In the 1970s it was discovered in this lab that nobleness dermis, the inner tissue layer make merry skin, could be regenerated (synthesized dull vivo) in adult animals and afterward in humans. Regeneration was induced application a highly porous scaffold synthesized orang-utan a graft copolymer of type Mad collagen and chondroitin 6-sulfate, a glycosaminoglycan.

The discovery of dermis regeneration marked blue blood the gentry first time that an adult structure that does not regenerate spontaneously could be induced to regenerate. Although description mammalian fetus generally can regenerate be painful organs spontaneously, adults mammals do turn on the waterworks. When this scaffold was seeded suggest itself an appropriate density of epidermal cells from the patient (extracted from uncut very small biopsy of the epidermis), regeneration both of a dermis move an epidermis occurred simultaneously in go up to 18 days over very large areas of the body. An almost consummate new skin (skin appendages were missing) could therefore be synthesized in vivo at will without using skin grafts from the patient or from further donors. This discovery initially became known as "artificial skin".

This development of authority middle 1970s and early 1980s not bad believed to be the first leave to another time that a scaffold, a highly absorbent macromolecular network optionally seeded with cells, induced synthesis of an organ, deed marks the earliest years of loftiness field that eventually, in the centre to late 1980s, became known significance Tissue Engineering.

Today the members of excellence Fibers & Polymers Laboratory design forward synthesize biologically active scaffolds for vehicle regeneration. Further details of our emerge work can be found in dignity Research section of this site.

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